AmedNews - 革新的がん研究支援室（PRIMO）ポータルサイト

AMED news

2019.08.22: Meflin-positive cancer-associated fibroblasts inhibit pancreatic carcinogenesis
2019.08.20: Pathogenic Epigenetic Consequences of Genetic Alterations in IDH-wild-type Diffuse Astrocytic Gliomas
2019.08.09: The new-generation selective ROS1/NTRK inhibitor DS-6051b overcomes crizotinib resistant ROS1-G2032R mutation in preclinical models
2019.07.30: Divergent lncRNA MYMLR regulates MYC by eliciting DNA looping and promoter‐enhancer interaction
2019.07.17: Molecular Mechanism of Cellular Oxidative Stress Sensing by Keap1
2019.07.03: Fibroblast growth factor signals regulate transforming growth factor‐β‐induced endothelial‐to‐myofibroblast transition of tumor endothelial cells via Elk1
2019.06.21: Allocation of the first adjustment expenses related to R&D in the medical field for FY2019
2019.05.18: Macrocyclic peptide-based inhibition and imaging of hepatocyte growth factor
2019.05.01: De novo DNA methylation at imprinted loci during reprogramming into naive and primed pluripotency
2019.04.30: Molecular dynamics simulation-guided drug sensitivity prediction for lung cancer with rare EGFR mutations
2019.04.25: Joint development of a new drug targeting pancreatic cancer
2019.03.29: LC-SCRUM-Japan expands screening to Taiwan
2019.03.25: Experimental screening conducted in Hokkaido
2019.03.14: Secreted PD-L1 variants mediate resistance to PD-L1 blockade therapy in non-small cell lung cancer
2019.03.06: Regnase-1-mediated post-transcriptional regulation is essential for hematopoietic stem and progenitor cell homeostasis
2019.03.06: Human Pluripotent Stem Cell-Derived Tumor Model Uncovers the Embryonic Stem Cell Signature as a Key Driver in Atypical Teratoid/Rhabdoid Tumor
2019.02.20: A role for IL-34 in osteolytic disease of multiple myeloma
2019.02.13: Strong therapeutic effects confirmed in physician-led clinical trials of viral therapy for brain tumors
2019.02.04: Interleukin-13 receptor α2 is a novel marker and potential therapeutic target for human melanoma
2019.01.30: Prediction of ALK Mutations Mediating ALK-TKIs Resistance and Drug Re-purposing to Overcome the Resistance
2019.01.25: Targeting the Vulnerability of Glutathione Metabolism in ARID1A-Deficient Cancers
2019.01.24: JCRP Cancer Symposium for Citizens held on February 23, 2019
2019.01.16: AXL confers intrinsic resistance to osimertinib and advances the emergence of tolerant cells
2019.01.11: Comprehensive molecular and immunological characterization of hepatocellular carcinoma
2018.12.26: Semaphorin signaling via MICAL3 induces symmetric cell division to expand breast cancer stem-like cells
2018.12.18: Loss of KDM6A characterizes a poor prognostic subtype of human pancreatic cancer and potentiates HDAC inhibitor lethality
2018.12.06: Supportive care/palliative treatment research policy (overview) released
2018.11.22: Allocation of second adjustment expenses related to R&D in the medical field for FY2018
2018.11.19: Serum level of soluble CD163 may be a predictive marker of the effectiveness of nivolumab in patients with advanced cutaneous melanoma